#1705897 CBC’s: A Small Price to Pay to Avoid the Intensive Care Unit for Methimazole Induced Agranulocytosis

Graves' disease is an autoimmune disorder that induces excessive thyroid hormone production. Thionamides are typically used for treatment but in rare circumstances can result in agranulocytosis. We present the case of a patient who was initiated on methimazole for treatment of Graves' disease, resulting in agranulocytosis, with subsequent Serratia marcescens bacteremia and septic shock.