#1691037 Ectopic Cushing Syndrome from Adrenocorticotropic Hormone - Secreting Small Cell Lung Cancer Presenting as Refractory Hypokalemia

Ectopic Cushing Syndrome (ECS) is a rare paraneoplastic syndrome characterized by hypercortisolemia caused by non-pituitary tumors producing large amounts of adrenocorticotropic hormone (ACTH). The case presented here is unique in that ECS, beyond its typical presentation of hyperglycemia, can manifest as refractory hypokalemia, resistant hypertension, and metabolic alkalosis.