Bacterial Profile of Urinary Tract Infection and Antimicrobial Susceptibility Pattern among the Patients attending a Tertiary Care Centre

Urinary Tract Infection (UTI) is a most cause of health issues in the world. It is the major cause of morbidity and mostly caused by bacterial infections from children to adults estimating the prevalence of UTI. To study the bacterial profile of urinary tract infection among the patients attending in a tertiary care center and also to assess the antimicrobial susceptibility patterns of the bacterial isolates. This study was conducted in the Pondicherry Institute of Medical Science Hospital, Pondicherry from 1st December 2020 to 30th January 2021. A total of 200 midstream urine samples were collected from suspected UTI patients attending in tertiary care settings. Urine samples were inoculated and the isolates were identified according to the standard microbiological techniques. The antimicrobial susceptibility tests were performed by Kirby-Bauer disk diffusion method on Mueller-Hinton agar according to the CLSI guidelines. Out of 200 samples, 107 positive urine cultures, UTI caused more in females (56%) when compared to males (44%). The most common bacteria frequently identified in this study were E.coli (57%) and followed by (12.15%) from gram negative isolates while Enterococcus species (7.48%) were common pathogen in gram positive organisms. The gram negative isolated were >70% sensitive to Amikacin, Nitrofurantoin and Piperacillintazobactam while >70% resistant to ampicillin, Nitrofloxacin and Cefazolin. The Gram positive isolates were 100% sensitive Vancomycin and Linezolid. The multi-drug resistance (MDR) was seen in most of the isolates. This study found a number of bacterial isolates with very high resistance to the commonly prescribed drugs from the patients with and without symptoms of UTI.