D40. Existing Psychiatric Diagnoses Interact with Outcomes after Autologous and Implant-based Breast Reconstruction: A Propensity Score Matched Analysis

PURPOSE: Breast reconstruction is an integral post-oncologic procedure that has been associated with improved mental health and psychological outcomes. The possible interaction between existing psychiatric diagnoses and hospital course and postoperative complications warrants further exploration. METHODS: Bilateral breast reconstruction patients were identified from the 2016-2018 Healthcare Cost and Utilization Project-National Inpatient Sample (HCUP - NIS). Number and type of psychiatric diagnoses within the cohort were then evaluated using a host of ICD-10 codes. A propensity score analysis was applied to control for confounding variables such as demographics, existing comorbidities, and hospital characteristics. A binary logistic regression model was then used to identify the prediction value of psychiatric diagnosis and its interaction with modality of reconstruction for objective outcomes like length of hospital stay, treatment charge, and postoperative complications. RESULTS: 10,114 patients were identified as the final cohort of breast reconstruction patients. 2,621 (25.9%) patients possessed an average of 1.4±0.6 existing psychiatric diagnoses. Presence of at least one psychiatric diagnosis was a strong predictor alone for extended length of stay (OR: 1.34, 95% CI: 1.28-1.41, p<0.001) and occurrence of postoperative complications (OR: 1.31, 95% CI: 1.21-1.41, p<0.001). Psychiatric diagnosis displayed a significant interaction with modality of breast reconstruction and conferred a lower increase in risk of extended length of stay in autologous reconstruction when compared to implant-based reconstruction (OR: 0.80, 95% CI: 0.72-0.89, p<0.001). CONCLUSION: Existing psychiatric diagnoses were shown to strongly predict and modulate risk of adverse postoperative outcomes depending on modality of reconstruction.