Hemodynamic Changes in Elective Cesarean Section, Under Spinal Anesthesia: A Prospective Randomized Controlled Double-Blind Comparison Study with Preoperative Ondansetron Administration

The most widely used anesthesia technique for cesarean delivery is the spinal anesthesia (SA). In Bnai-Zion Medical Center over than 90% of the elective cesarean sections performed under SA. However, this type of anesthesia frequently associated with side effects that primarily affect the parturient and the fetal health 1. Nearly, 70-80% of obstetric patients experience spinal anesthesiainduced hypotension (SAIH) without pharmacological prophylaxis 2. This hypotension is commonly accompanied with reflex tachycardia, nausea and vomiting, and in rare occasions bradycardia can be observed. Most authors agree that hypotension presents when systolic blood pressure (SBP) reduced from baseline of more than 20% 3. The main mechanism of SAIH is decreased systemic vascular resistance resulting from arterial vasodilation 4.