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Antibody-mediated rejection is a leading cause of kidney-transplant failure. The targeting of CD38 to inhibit graft injury caused by alloantibodies and natural killer (NK) cells may be a therapeutic option.
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Katharina A Mayer
Eva Schrezenmeier
Matthias Diebold
University of Basel
New England Journal of Medicine
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Mayer et al. (Sat,) studied this question.
synapsesocial.com/papers/68e686b9b6db64358760f0c1 — DOI: https://doi.org/10.1056/nejmoa2400763