The Impact of Occupational Exposure on Workers’ Respiratory Microbiota

firstₚage Download PDF settings Order Article Reprints Font Type: Arial Georgia Verdana Font Size: Aa Aa Aa Line Spacing:    Column Width:    Background: Open AccessAbstract The Impact of Occupational Exposure on Workers' Respiratory Microbiota † by Sandra LavandeiraSandra Lavandeira SciProfiles Scilit Preprints. org Google Scholar 1, 2, *, Marta OliveiraMarta Oliveira SciProfiles Scilit Preprints. org Google Scholar 1, Maria José AlvesMaria José Alves SciProfiles Scilit Preprints. org Google Scholar 2, 3 and Simone MoraisSimone Morais SciProfiles Scilit Preprints. org Google Scholar 1 1 REQUIMTE/LAQV, ISEP, Polytechnic of Porto, 4249-072 Porto, Portugal 2 AquaValor—Center for Valorization and Transfer of Water Technology, 5400-342 Chaves, Portugal 3 CIMO, Polytechnic of Bragança, 5300-253 Bragança, Portugal * Author to whom correspondence should be addressed. † Presented at the 1st International Electronic Conference on Toxics, 20–22 March 2024; Available online: https: //sciforum. net/event/IECTO2024. Proceedings 2024, 102 (1), 34; https: //doi. org/10. 3390/proceedings2024102034 Published: 3 April 2024 Download keyboardₐrrowdown Download PDF Download PDF with Cover Download XML Download Epub Versions Notes Keywords: microbiome; microbiota; respiratory tract; occupational exposure; dysbiosis 1. IntroductionSeveral recent studies have demonstrated that occupational exposure to chemical and biological pollutants alters the human microbiome. Considering that the respiratory tract is one of the main entry points for foreign substances into the body, this small review aims to explore the effects that different occupational exposures have on workers' respiratory microbiota. 2. MethodologyA PRISMA-based systematic review search was carried out in Scopus, Medline (PubMed), and Web of Science databases, through a combination of the following keywords utilizing the operators "AND" and "OR": "microbiome", "microbiota", "respiratory tract", "airways", "nasal", "occupational", and "worker". 3. Results and DiscussionAmong the selected studies, exposure to biological agents via agricultural or health professionals was the most studied occupational risk factor and was found to lead to changes in the workers' microbiota. Changes in oral and nasal microbiota were also detected in workers exposed to chemical agents such as farm workers exposed to pesticides, cooks exposed to fumes, and facility workers exposed to phthalates. More studies are needed to understand the role of occupational exposure in changing the microbiota of the respiratory tract and the health risks associated with this change. 4. ConclusionsThis review highlights how occupational exposure to different chemical or biological agents can promote the dysbiosis of the respiratory microbiota. This dysbiosis affects the host's immune response and contributes to the development of respiratory diseases. Author ContributionsConceptualization, S. L. , M. O. , M. J. A. and S. M. ; methodology, S. L. and M. O. ; validation, M. O. , M. J. A. and S. M. ; formal analysis, S. L. , M. O. , M. J. A. and S. M. ; data curation, S. L. and M. J. A. ; writing—original draft preparation, S. L. ; writing—review and editing, S. L. , M. O. , M. J. A. and S. M. ; supervision, M. O. , M. J. A. and S. M. ; funding acquisition, M. O. and S. M. All authors have read and agreed to the published version of the manuscript. FundingThis work was financially supported by the project PCIF/SSO/0017/2018, by the Fundação para a Ciência e Tecnologia (FCT) and Ministério da Ciência, Tecnologia e Ensino Superior (MCTES) through national funds. Institutional Review Board StatementNot applicable. Informed Consent StatementNot applicable. Data Availability StatementNo new data were created in this study. Data sharing is not applicable to this article. AcknowledgmentsThis work received support from UIDB/50006/2020, UIDP/50006/2020, LA/P/0008/2020, PCIF/SSO/0090/2019, and 2022. 05381. PTDC by FCT-MCTES. M. Oliveira and S. Lavandeira thank, respectively, the Individual Program Agreement CEECIND/03666/2017 and the PhD grant (2022. 12979. BDANA), funded by the FCT-MCTES. Conflicts of InterestThe authors declare no conflict of interest. Disclaimer/Publisher's Note: The statements, opinions and data contained in all publications are solely those of the individual author (s) and contributor (s) and not of MDPI and/or the editor (s). MDPI and/or the editor (s) disclaim responsibility for any injury to people or property resulting from any ideas, methods, instructions or products referred to in the content. © 2024 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https: //creativecommons. org/licenses/by/4. 0/). Share and Cite MDPI and ACS Style Lavandeira, S. ; Oliveira, M. ; Alves, M. J. ; Morais, S. The Impact of Occupational Exposure on Workers' Respiratory Microbiota. Proceedings 2024, 102, 34. https: //doi. org/10. 3390/proceedings2024102034 AMA Style Lavandeira S, Oliveira M, Alves MJ, Morais S. The Impact of Occupational Exposure on Workers' Respiratory Microbiota. Proceedings. 2024; 102 (1): 34. https: //doi. org/10. 3390/proceedings2024102034 Chicago/Turabian Style Lavandeira, Sandra, Marta Oliveira, Maria José Alves, and Simone Morais. 2024. "The Impact of Occupational Exposure on Workers' Respiratory Microbiota" Proceedings 102, no. 1: 34. https: //doi. org/10. 3390/proceedings2024102034 Article Metrics No No Article Access Statistics Multiple requests from the same IP address are counted as one view.