The incidence rate of hyperuricemia and association with food habits during a 10-year cohort study. Yazd Healthy Heart Cohort

Abstract Hyperuricemia (HUA) has increased in adults in the past few years. This study investigates HUA incidence and its association with food habits during a 10-year cohort study in Yazd province. This retrospective cohort study (Yazd Healthy Heart Cohort (YHHC)) was conducted in 2005–2006. One thousand nine hundred eighty-five people aged 20–74 were followed for ten years. Data were analyzed using SPSS-22 software. A Binary logistic regression was used in modeling. Confidence intervals for incidence were also calculated using the Stata 13 software. The significance level was set as p < 0.05. The cumulative incidence rate of HUA in all individuals, males and females, was 17.3%, 16.4%, and 18.4%, respectively.OR and RR of HUA were (OR= 1.59 & RR=1.40) in abnormal waist circumference (WC) (P=0.02), (OR= 1.88 & RR= 1.55) in fast food consumers (P=0.009) and (OR= 0.48 & RR=0.68) in people with a high socioeconomic level (p=0.02). Abnormal WC and fast food consumption are risk factors for HUA. The high socioeconomic level is one of the protective factors of HUA.