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Given the significant interest in medicinal plants and their use in medicine, the question of finding new promising plants or using long-known plants in a new way is relevant. The growing demand for phytomedicines and the trend for all things natural encourage the search for new plant species that can be a source of biologically active substances. One of the promising genus for detailed pharmacognostic analysis is the genus Tagetes, which is widely used in Ukraine, is used as a drug to treat various health problems, including dental, gastric, intestinal, emotional and nervous disorders. The aim of the work was to analysis and generalization of scientific information on the distribution, chemical composition, pharmacological activity and potential of medical applications of plants of the genus Tagetes. Methodology used in the review is based on the analysis of published original research articles through exhaustive search through scientific databases such as MEDLINE/PubMed and Google Scholar using different key words as «marigolds», «medicinal use», «pharmacological activity», «phytochemistry», «Tagetes». The criteria for including publications in the analytical review were: a) language of publication – English, Ukrainian; b) availability of abstract; c) availability of the full publication in free access. The genus Marigold is part of the family Compositae (Asteraceae) and includes almost 56 species of plants that are distributed around the world and in Ukraine and are usually cultivated as ornamental plants. The plants of this genus are unofficial; they are used in folk medicine of different countries because they have antibacterial, anti-inflammatory, reparative, hepatoprotective, antioxidant, antitumor, maculoprotective activity. The main biologically active substances of the plant include carotenoids, flavonoids and essential oils and compounds of phenolic nature. In addition, different species of marigolds are studied in agriculture for their fungicidal, bactericidal and insecticidal activity. Analysis of world experience in the use of plants of the genus Tagetes in folk medicine, experimental studies on the phytochemical composition of plants of this genus and a wide range of their pharmacological activity showed that the aboveground organs of different species of plants of the genus Tagetes (T. patula, T. erecta, T. minuta) can be considered as promising raw materials for further research.
Богату et al. (Fri,) studied this question.