Peptide Therapy Update

Peptides are short chains of amino acids which are versatile and specific. Their specificity, ability to mimic natural functions, and reduced side effects compared to traditional drugs make them attractive for treating various diseases. Already, 15 peptide drugs have been approved by the FDA, with hundreds more in clinical trials for applications like cancer, autoimmune disorders, and infections. Peptides can have a few drawbacks which can include: the delivery of the peptides, which increases the cost, and further reducing the accessibility of the treatment. However, the future is promising as personalized peptides can be created which are made from specific genetic profiles, being able to be synergized with conventional drugs to enhance effects, and utilizing advanced deliver systems which can release controlled and targeted peptides. This review highlights the versatility of peptides, exploring their mechanisms and current roles in diverse medical fields.