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Primary splenic angiosarcoma is an uncommon and fatal cancer that affects 2 out of every 10 million people worldwide, according to epidemiological incidence rates.For primary spleen angiosarcoma, there are not enough systematic clinical data available, there have been only 90 cases reported since 1950.In this study, we analyzed 25 publications published between January 1950 and November 2022, providing thorough information on 52 cases of main spleen angiosarcoma.We also described a case of primary spleen angiosarcoma with metastases to the liver and bone.This study will go into great length on the etiology, clinical manifestations, laboratory and pathological features, and available treatments for primary spleen angiosarcoma, with the purpose to provide a thorough review and guidance for clinical guidance of this rare disease.
Wang et al. (Tue,) studied this question.