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Postoperative spinal infections following lumbar fusion with posterior lumbar interbody fusion (PLIF) are a concerning complication, particularly in cases of degenerative spinal disease. However, factors contributing to infection risk remain unclear. This retrospective study analyzed data from 124 adults who underwent instrumented fusion for degenerative spinal conditions between 2015 and 2020. Multivariate proportional hazards regression identified risk factors associated with surgical site infections (SSI). Results revealed a 16.9% incidence of SSI, with 92.4% of cases showing positive microbiological cultures. Prolonged hospital stay, prior surgeries, advanced age, diabetes, and obesity were correlated with infection risk. Notably, 95% of infected patients were successfully treated with surgical intervention or antibiotics without hardware removal. This underscores the importance of early identification and intervention in managing postoperative spinal infections, mitigating the need for hardware removal and improving patient outcomes.
Kareem et al. (Sun,) studied this question.