Epigenetic regulation of glucosinolate biosynthesis sees the light of day

Glucosinolates (GSL) are specialized defense metabolites synthesized by species of the order Capparales including the economically important Brassicaceae crops such as oil seed rape, cabbages and kales.Upon ssue damage, GSLs stored in the vacuole are degraded by myrosinases together with specifier proteins.The breakdown products include thiocyanates, isothiocyanates, nitrile and epithionitriles which are toxic to pathogens and herbivores (Wi stock Wu et al., 2023).137 different GSL structures have been iden fied in various species and divided into three subcategories, alipha c glucosinolates, indole glucosinolates and benzyl glucosinolates, according to the amino acid precursor used in their biosynthesis (Blazevic et al., 2020).The GSL biosynthe c pathways have been extensively studied in the model plant Arabidopsis thaliana (herea er Arabidopsis).GSL biosynthesis is composed of three phases that include chain elonga on, core structure forma on and side chain modifica on that results in a variety of different compounds with nitrogen and sulfur containing core structure and highly variable side chain (Blazevic et al., 2020).