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Scanning Transmission Electron Microscopy (STEM) coupled with Electron Energy Loss Spectroscopy (EELS) presents a powerful platform for detailed material characterization via rich imaging and spectroscopic data. Modern electron microscopes can access multiple length scales and sampling rates far beyond human perception and reaction time. Recent advancements in machine learning (ML) offer a promising avenue to enhance these capabilities by integrating ML algorithms into the STEM-EELS framework, fostering an environment of active learning. This work enables the seamless integration of STEM with High-Performance Computing (HPC) systems. We present several implemented workflows that exemplify this integration. These workflows include sophisticated techniques such as object finding and Deep Kernel Learning (DKL). Through these developments, we demonstrate how the fusion of STEM-EELS with ML and HPC enhances the efficiency and scope of material characterization for 70% STEM available globally. The codes are available at GitHub link.
Pratiush et al. (Sun,) studied this question.