Key points are not available for this paper at this time.
Case DesCriptionA 19-year-old female, a known case of type 1 diabetes mellitus, presented to our hospital with complaints of fever, cough, and shortness of breath, which started nearly 1 week ago but gradually introDuCtion Hypereosinophilic syndrome (HES) is a rare multisystem disorder characterized by persistent, significant eosinophilia and associated organ dysfunction, leading to substantial morbidity and mortality.A consensus definition developed by a multidisciplinary group of experts defines HES as follows 1,2 :• Hypereosinophilia: An absolute eosinophil count (AEC) exceeding 1,500 cells/μL.• Eosinophil-mediated organ damage: Clear evidence of damage to organs due to eosinophil activity.• Exclusion of other causes: A thorough exclusion of all other potential causes of hypereosinophilia.Alternatively, tissue hypereosinophilia can be identified in addition to an elevated AEC.Tissue hypereosinophilia is defined by:• Bone marrow involvement: Eosinophils constitute >20% of nucleated cells in the bone marrow.• Extensive tissue infiltration: Significant eosinophil infiltration in target organs as evidenced by histological analysis.• Eosinophil degranulation: Histological evidence of eosinophil degranulation in a target tissue in the absence of eosinophils in that tissue.In this report, we present the case of a young female who developed eosinophilic pneumonia, deep vein thrombosis (DVT), cerebral venous sinus thrombosis (CVST), and immune thrombocytopenia (ITP).Her condition was successfully managed with a combination of steroids, intravenous immunoglobulin, and anticoagulation therapy.
Selvam et al. (Thu,) studied this question.