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Aim: This retrospective analysis aimed to evaluate the comparative efficacy of osteochondral autologous transplantation (OAT) versus autologous matrix-induced chondrogenesis (AMIC) in the management of osteochondral lesions of the talus (OLT). Materials and Methods: In this retrospective cohort study, 55 individuals (24 males, 31 females) with an average age of 40.7 ± 12.6 years (range 18-66 years) were included. The study assessed 59 ankles in total due to 4 patients undergoing bilateral procedures at separate intervals. Of these, 22 were treated using AMIC and 37 received OAT. Functional outcomes were assessed using the American Orthopaedic Foot and Ankle Society (AOFAS) scale preoperatively and at the latest follow-up. The Lysholm Knee Score was utilized for evaluating knee function in patients subjected to OAT. Serial radiographic examinations of the ankle were conducted to assess osteotomy union, reduction loss, graft subsidence, and progression of osteoarthritis (OA) using the Kellgren-Lawrence grading system for post-treatment OA evaluation. Results: Comparative analysis revealed no statistically significant differences between AMIC and OAT in terms of improvement in AOFAS scores (p=0.467), progression of OA (p=0.141), or complication rates (p=0.373). Conclusion: Both AMIC and OAT present as effective therapeutic options for OLT, with comparable success rates and outcomes.
Eğerci et al. (Wed,) studied this question.