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Background: Healthcare-associated infections (HAIs) are a significant healthcare burden in Canada.National surveillance of HAIs at sentinel acute care hospitals is conducted by the Canadian Nosocomial Infection Surveillance Program.Objective: This article describes device and surgical procedure-related HAI epidemiology in Canada from 2018 to 2022.Methods: Data were collected from over 60 Canadian sentinel acute care hospitals between January 1, 2018, and December 31, 2022, for central line-associated bloodstream infections (CLABSIs), hip and knee surgical site infections (SSIs), cerebrospinal fluid shunt (CSF) SSIs and paediatric cardiac SSIs.Case counts, rates, patient and hospital characteristics, pathogen distributions and antimicrobial resistance data are presented.Results: Between 2018 and 2022, 2,258 device-related infections and 987 surgical procedurerelated infections were reported.A significant rate increase was observed in adult mixed intensive care unit CLABSIs (1.07-1.93infections per 1,000 line days, p=0.05) and a nonsignificant rate increase was observed in SSIs following knee arthroplasty (0.31-0.42 infections per 100 surgeries, p=0.45).A fluctuating rate trend was observed in CSF shunt SSIs over the time period and a significant rate decrease in paediatric cardiac SSIs was observed (68%, from 7.5-2.4infections per 100 surgeries, p=0.01).The most commonly identified pathogens were coagulase-negative staphylococci (22.8%) among CLABSIs and Staphylococcus aureus (42%) among SSIs. Conclusion:Epidemiological and microbiological trends among selected device and surgical procedure-related HAIs are essential for benchmarking infection rates nationally and internationally, identifying any changes in infection rates or antimicrobial resistance patterns and helping inform hospital infection prevention and control and antimicrobial stewardship policies and programs.
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