Zebrafish embryos exhibited mortality, altered hatchability, and developmental abnormalities following tributyltin exposure

Various endocrine system regulations, like homeostasis and physiological coordination, alter due to the effects of various xenobiotic chemicals in marine ecosystems 1.Tributyltin, an endocrine disruptor that poses a threat to the environment, is used as a fungicide in the wood and plastic industry, and as an antifouling agent to be coated on ship hulls 2.TBT is detected at high levels in some water samples because of its long half-life and extensive unlawful use 3,4.Due to the significant negative effects on aquatic life, the possibility of aquatic contamination caused by TBT use has been of great concern 5.Zebrafish embryos are transparent in the early stages of development, and their eggs are fertilized outside which helps to explore the developmental toxicology 6,7.Rapid development and external post-fertilization make embryos more vulnerable to environmental influences and make it easier to observe anatomical malformation, hatching rate, and other