Microwave-Assisted Synthesis of Heterocyclic Scaffolds

Abstract In recent years, there has been a notable surge in the utilization of microwave energy, leading to the emergence of innovative and groundbreaking methods across various branches of chemistry, including organic synthesis, materials science, heterocyclic chemistry, and medicinal chemistry. This comprehensive literature review delves into the microwave-assisted organic synthesis of specific heterocycles, illuminating its effectiveness in producing diverse molecules with heightened efficiency and selectivity. The review highlights the significant role of microwave irradiation as a potent method for constructing a wide range of compounds. Particular emphasis is placed on the impact of the technique on synthesizing various hybrids such as 1,2,3-triazole hybrids, coumarin hybrids, imidazopyridine hybrids, phenanthridines hybrids, carbene hybrids, and oxazole hybrids. This article is valuable as it offers insights into current synthetic procedures and trends in developing innovative medications utilizing heterocyclic compounds. 1 Introduction 2 Synthesis of 1,2,3-Triazole Hybrids 3 Coumarin Hybrids 4 Imidazo Pyridine Hybrids 5 Phenanthridine Hybrids 6 Carbene Hybrids 7 Oxazole Hybrids 8 Conclusion