Aspartate Aminotransferase (Ast) to Platelet Ratio Index (Apri) Non Invasive Marker for Evaluation of Probable Fibrosis in Alcoholic Liver Disease

Background: Alcoholic liver disease (ALD) is a major cause of liver disease caused by excessive alcohol intake. Liver brosis is most common complication of ALD. Diagnosis of brosis is usually invasive procedure or radiological procedure which is expensive. Hence this study was conducted to evaluate the use of APRI in ALD cases which is non- invasive procedure. Material And Methods: Observational study was conducted on 70 patients evaluated from medical ward, Deaddiction center. Result: Using APRI Cirrhosis was seen in 11(15.71%), Fibrosis in 23(32%), No Fibrosis in 36(51%).Out 11 cases of cirrhosis by APRI, 04 has shown hepatitis and 01 shown fatty liver by USG. Out of 23 cases of Fibrosis by APRI , 08 cases has shown hepatitis ,13 cases has shown fatty liver, 02 cases shown cirrhosis by USG. Out of 36 cases of No brosis by APRI has shown fatty liver by USG. Conclusion: The present study thus highlights the importance of nonnon-invasive method for diagnosis of brosis