P-496 Chronic Obstructive Pulmonary Disease (Copd) and Occupational Exposures: The Case of Morocco

Abstract Introduction Occupational exposures are an important cause of chronic obstructive pulmonary disease (COPD). This work aims to analyze the epidemiological evidence on the association between occupational exposures, the development and aggravation of COPD, with a particular focus on Morocco. Methods Scientific databases were searched for studies reporting data on COPD and workplace exposures. Results Data from the published literature show that occupational exposures play an important role in the development of COPD. Positive correlations have been established between occupational exposures and the prevalence and incidence of COPD. In addition, occupational exposures have a negative impact on COPD patients, resulting in increased frequency of respiratory symptoms and exacerbations, reduced spirometric parameters and impaired quality of life. In Morocco, the link between occupational exposure and COPD has not been sufficiently studied. Discussion A limited number of studies have suggested that construction workers and former miners are at high risk of developing COPD. No studies investigating the effect of occupational exposure to dusts, vapors, gasses and fumes on the health status of COPD patients in Morocco were found. Conclusion Occupational exposure is a potential risk factor in the development and aggravation of COPD. In Morocco, this link has not been sufficiently studied. Consequently, it is time for more in-depth studies aimed at identifying at-risk occupations, assessing the exposure-response relationship, and determining the exposure limits that should be retained to guide COPD prevention and management strategies nationwide.