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Breast cancer, the most common cancer among women globally, affects all age groups, with treatment decisions varying significantly between young and elderly patients due to factors such as toxicity, pregnancy, future fertility, perceived aggressiveness, life expectancy, and comorbidities. This retrospective descriptive study at the National Institute of Oncology in Rabat, covering women diagnosed between January 2019 and December 2021, included 257 women under 40 and 117 women aged 70 and older. The findings revealed that younger women often had fewer comorbidities and faced more aggressive tumors with higher lymph node involvement, while elderly women, with a higher prevalence of comorbidities (especially cardiovascular and endocrine), showed greater treatment refusal rates, particularly for chemotherapy, radiotherapy, and adjuvant endocrine therapy. These differences underscore the necessity of personalized treatment strategies to address the specific needs and concerns of both age groups, aiming to enhance clinical outcomes and quality of life.
- et al. (Fri,) studied this question.