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Soft materials, particularly elastomers, are extensively studied, but investigations into purely soft gel contact systems are limited due to their complex dual phases consisting of polymer and free liquids. While Dual Wavelength-Reflection Interference Confocal Microscopy (DW-RICM) is effective for noninvasively visualizing interfaces from a bottom view, it faces challenges in gel studies due to close refractive indices of polymeric networks and free liquids. We hypothesize that modulating the refractive index of soft gels using nanoparticles (NPs) enhances the visualization of contact zone beneath the free surface, providing insights into the configuration of phase-separated free oil within gel-on-gel contact systems. Gel-on-gel contact systems were fabricated using immiscible organogels and hydrogels. Titanium dioxide (TiO2) NPs were introduced into the organogel to modulate refractive indices. Given the lack of prior studies on the hidden contact zone between gels, various techniques, including DW-RICM, side-view imaging, and inverted optical microscopy, were employed to observe and validate our findings. Comparative analyses were conducted with elastomer-on-rigid, elastomer-on-gel, and gel-on-rigid contact systems. Our investigation demonstrated that a minimal amount of TiO2 NPs effectively delineates the direct contact radius between organogel polymeric networks and hydrogel surfaces. Comparative experiments showed that TiO2 addition did not alter the gels' mechanical and surface properties but significantly enhanced information on gel contact deformation. This enhanced visualization technique has the potential to advance our understanding of adhesive contacts in gels, providing valuable insights into interface phenomena involving biological soft tissues and cells.
Kim et al. (Sun,) studied this question.