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In recent years, the growing interest in liquid chromatography-mass spectrometry (LC-MS) in the food safety area has resulted in various innovative and promising applications. This comprehensive review aims to examine both sample preparation and LC-MS strategies within the field of chemical contaminants in food. The exploration entails an extended investigation of peer-reviewed literature over the past decade, specifically focusing on methodologies tailored for the determination of veterinary drugs and pesticides. Furthermore, relevant development and applications of LC-MS screening methods are overviewed, accentuating their strengths and limitations. Prospective directions for advancing LC-MS methodologies in this field are included to help researchers select the most appropriate screening analytical method.
Brandi et al. (Wed,) studied this question.