Abstract 2125: Aneurysmal Disease Among Hospitalized Patients With Fibromuscular Dysplasia - Types And Prevalence: Findings From The National Inpatient Sample

Introduction: Fibromuscular dysplasia (FMD) is a non-atherosclerotic, non-inflammatory disease that can lead to various arterial abnormalities, including dissection, occlusion, and aneurysm. Only a few studies have examined the common types of aneurysmal disease among patients with FMD. We examine the types and prevalence of aneurysmal disease among hospitalized patients with FMD. Methods: Using the International Classification of Diseases, 10th edition, Clinical Modification (ICD-10-CM) diagnosis codes, we queried the National Inpatient Sample 2016 to 2020 for hospitalizations among patients ≥18 years old with a diagnosis of Fibromuscular dysplasia. Aneurysmal disease of the iliac, carotid, upper extremity, lower extremity, renal, vertebral artery, thoracic aorta, and abdominal aorta was further identified in this cohort of patients using ICD-10 codes. We examined prevalence of FMD and further compared the prevalence of aneurysmal disease among hospitalized patients with and without FMD. Results: Our study included 9,315 weighted hospitalizations among patients with fibromuscular dysplasia (mean SD age 61.2 15.5 years). FMD was five times more common in females than males (84.1% vs. 15.9%). Compared to hospitalized patients without FMD, aneurysmal disease was more common among hospitalized patients with FMD. The most common aneurysmal site among patients with and without FMD was the renal artery (1.4%) and abdominal aorta (0.71%) respectively. The prevalence of aneurysmal disease among hospitalized patients with FMD was renal artery aneurysm (1.40%), abdominal aortic aneurysm (1.29%), carotid artery aneurysm (1.23%), thoracic artery aneurysm (1.02%), vertebral artery aneurysm (0.86%), lower extremity artery aneurysm (0.38%), iliac artery aneurysm (0.27%), and upper extremity artery aneurysm (0.16%). Conclusion: Aneurysmal disease is prevalent among hospitalized patients with Fibromuscular dysplasia, with the renal artery identified as the most common site of aneurysm. Further research is needed to understand better the relationship between FMD and other vascular abnormalities.