Ultrasound-guided inferior vena cava collapsibility index as a predictor of fluid responsiveness in septic cancer patients

Background whereas MAP, CVP, and CO increased significantly. ROC-curve analysis showed a percent change ≥ 3.4% of IVC-CI predicted positive responsiveness with a sensitivity of 72.4% and a specificity of 63.6%. These values were 79.3% and 72.7%, respectively, for a change ≥ 6.3% after one hour. The baseline value of IVC-CI was not predictive of responsiveness. Conclusion: In cancer patients with sepsis or septic shock, the change in inferior vena cava collapsibility index during the first hour of fluid therapy can predict fluid responsiveness with a moderate degree of accuracy. Abbreviations: CO - Cardiac output; CVP - central venous pressure; IVC- inferior vena cava; IVC-CI - inferior vena cava collapsibility index; MAP - Mean arterial pressure; SV - Stroke volume Keywords: Cancer; ICU; Critically sick; Inferior vena cava; IVC collapsibility index; Non-invasive cardiometry; Sepsis Citation: Gaafar MA, Soliman AM, Ahmed NA, Kotb TA, Shaker EH. Ultrasound-guided inferior vena cava collapsibility index as a predictor of fluid responsiveness in septic cancer patients. Anaesth. pain intensive care 2024;28(3):547−552; DOI: 10.35975/apic.v28i3.2472 Received: March 20, 2024; Revised: March 23, 2024; Accepted: April 27, 2024