Development of Silk Fibroin Dressings and Advances in Their Application in Wound Healing

Wound healing is a complex process involving hemostasis, inflammation, proliferation, and remodeling phases. Medical wound dressings are commonly employed to promote wound healing, alleviate patient discomfort, and prevent further tissue inflammation or expedite wound closure. Among various wound dressings, silk fibroin dressings have garnered widespread attention due to their outstanding anti-inflammatory and hemostatic properties, as well as excellent biocompatibility. Therefore, this paper introduces the biological characteristics of silk fibroin, elucidates the current research status of silk fibroin-based wound dressings in various forms such as nanofibers, hydrogels, films, foams, and ointments, and discusses the challenges and future research directions in the field of silk fibroin-based dressings for wound repair, providing insights for further development and application of silk fibroin dressings.