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Marine algae contain diverse bioactive compounds with pharmaceutical and nutraceutical importance. The present study was aimed at exploring one such alga, Sargassum polycystum, belonging to the phaeophyceae family. The seaweed was extracted with two different solvent systems and subjected to phytochemical analysis, antimicrobial and antioxidant studies. The extract showed wide variety of phytocomposition and was found to possess significant antimicrobial activity against bacterial and fungal pathogens. For antioxidant activities, DPPH assay, Hydroxyl radical scavenging assays, Phosphomolybdenum reduction and Fe3+ reducing power assays were carried out. The extract exhibited remarkable antioxidant activity in all the assays, especially in Fe3+ reducing power assay and hydroxyl radical scavenging, a maximum inhibition of 96.27 and 84.14% was observed, respectively. Also, the GC-MS analysis further confirmed the presence of isoflavone, a phenolic compound that signifies the role in antioxidant activity.
Swetha et al. (Tue,) studied this question.