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Ocimum tenuiflorum L., commonly known as Holy Basil or Tulsi, is an ancient herb deeply rooted in Ayurvedic medicine. With over 5000 years of history, it holds religious, cultural, and medicinal significance in India, earning titles such as the "Elixir of Life" and "Queen of Herbs." This review explores the therapeutic applications of Holy Basil in psychiatry, neurodegenerative diseases, oncology, infections, and diabetes mellitus. Through an analysis of clinical and preclinical studies, we highlight the herb's multifaceted pharmacological properties, including antioxidant, anti-inflammatory, antimicrobial, and anticancer effects. Key bioactive compounds such as rosmarinic acid, eugenol, and ursolic acid contribute to its diverse therapeutic actions. This review draws upon data from databases such as PubMed, Scopus, and Google Scholar to comprehensively analyze existing literature. However, while existing research supports the efficacy of Holy Basil, further clinical trials using standardized preparations are warranted to validate its clinical utility. This review underscores the importance of Ocimum tenuiflorum as a promising complementary therapy in modern medicine and emphasizes the need for continued research to unlock its full potential.
Muszalska et al. (Mon,) studied this question.