Study of Correlation Between C- Reactive Protein and Glycemic Control in Patients With Type 2 Diabetes Mellitus and Correlate With Cardiac Complications.

Incidence of type 2 diabetes mellitus(T2DM) is increasing. It has become major risk factor for morbidity & mortality (1,2,3,). Many markers of glycaemic control Like Fasting & Postprandial Blood Sugar levels (FBSL & PP BSL), Glycated Haemoglobin (HbA1C)& C Reactive Protein(CRP). These can help to diagnose, treat & prevent complications. Of these high-sensitivity (hs-CRP) as an independent predictor of increased CVD (CVD) in T2DM (5,6,7). Aims: To study correlation between glycaemic control, CRP&CVD in patients ofT2DM. Objectives: 1. To study clinical prole, CRP,F BSL, HbA1C, Electrocardiogram (ECG) & 2 Dimentional echocardiography((2D ECHO) in patients with T2DM. 2. To correlate HbA1C, CRP &CVD in patients of T2DM. Material and methods: Study design -Descriptive study. Study population-All the patients of T2DM >18 yrs. attending Medicine Department at Bharati Hospital & Medical College, Sangli. Inclusion criteria: Diagnosed cases of T2DM above 18 yrs of age. Exclusion criteria: Patients on Statins, Thiazolididiones, Anti-inammatory drugs, Steroids. Known cases of Hemoglobinopathies, Malignancy. Study variables: Age, Sex, FBSL, HbA1c.ECG,2D ECHO. Sample size: Patient admitted in Bharati Hospital during study period Sampling technique: Purposive Sampling. Observation & Results- Our study concluded that,FBSL,HbA1C and CRPwere raised suggesting uncontrolled diabetic status. Even Waist Hip ratio was much altered in patients. Asignicant correlation was found between CRP levels and cardiac complications. The study has positive association between BMI& HbA1c levels. Also between FBSL levels and HbA1c levels. To summarise estimating CRPprovide a sensitive prediction of cardiovascular complexities inT2DM.