Navigating the Maze When Both Eyes Suffer : A Case Report of Valproic Acid Induced Bilateral Crvo in a Young Patient With Hyperhomocystinemia

Central retinal vein occlusion (CRVO) is one of a common cause of visual impairment. It commonly affects men and women equally and occurs predominantly in persons over the age of 65 years. In this population, there may be associated systemic vascular disease, including hypertension and diabetes. Younger individuals who present with clinical picture of CRVO may have underlying hypercoagulable or inammatory etiology. Sodium valproic acid is an antiepileptic drug extensively used for treating partial and generalised seizures, acute mania, and prophylaxis for bipolar disorder. VPA causes hepatotoxicity which in turn causes hypercoagulability. Drug induced liver injury(DILI) persists as signicant issue related to fatal outcomes by VPA. Here is a 35 yr old young patient with h/o intake of sodium valproate for 10 yrs, presented to our opd with B/L CRVO with hyperhomocysteine levels.