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Myocardial ischemia-reperfusion (MI/R) can lead to structural and functional abnormalities in the hippocampal neurons of the brain. High-mobility group box-l (HMGB1) is implicated in the activation of immune cells and the stimulation of inflammatory responses. However, the specific role of HMGB1 in cognitive impairment induced by MI/R in elderly rats has yet to be elucidated.
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Yang et al. (Sat,) studied this question.
synapsesocial.com/papers/68e5cc6bb6db643587562a79 — DOI: https://doi.org/10.1016/j.exger.2024.112540
Wenqu Yang
Jing Yu
Hui Wang
Rutgers, The State University of New Jersey
Experimental Gerontology
Shanxi Medical University
Shanxi Academy of Medical Sciences
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