Low-renin hypertension affects 1 in 4 hypertensive patients, requiring individualized treatment based on underlying pathophysiology due to expanding spectrums of causes and management strategies.
Low-renin hypertension requires individualized treatment based on underlying pathophysiology, as many patients do not fit traditional definitions of known causes.
Low-renin hypertension is common and affects 1 in 4 people with hypertension. Understanding the different causes and management of low-renin hypertension is becoming increasingly relevant as renin measurements are more widely ordered in clinical practice. Importantly, many people with low-renin hypertension do not fit traditional definitions of known causes, and the approach to management of these people is not unclear. This review provides an overview of our evolving understanding of the causes of low-renin hypertension, the expanding spectrums of pathophysiology, key differentiating characteristics, distinct management strategies, and highlights our knowledge gaps. It is important to distinguish the underlying pathophysiology of an individual with low-renin hypertension to individualize treatment.
Shah et al. (Tue,) conducted a review in Low-renin hypertension. Low-renin hypertension affects 1 in 4 hypertensive patients, requiring individualized treatment based on underlying pathophysiology due to expanding spectrums of causes and management strategies.
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