Ultra-high field characterisation of resting state networks in the neonatal brain

Acquiring BOLD fMRI data at ultra-high field offers marked gains in sensitivity and spatial specificity including within cortical layers and distinct subcortical nuclei. We describe the first pilot data demonstrating feasibility of characterizing resting state networks in the neonatal brain using a 7 Tesla system. In 3 neonates imaged at full term, we show that in addition to the canonical networks seen at standard field strengths, ultra-high field fMRI enables network delineation with higher spatial specificity, including better localization to the cortex and with definition of individual networks corresponding to distinct anatomical regions and tissues.