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MR thermometry based on the proton resonance frequency (PRF) shift is a widely used tool to monitor changes in tissue temperature in response to MR-guided thermal interventions. However, MR temperature mapping at low field (< 1T) is challenging because of reduced signal to noise ratio (SNR) and intrinsically low temperature-sensitivity of the PRF shift. In this work, we present a multi-contrast segmented EPI sequence for PRF thermometry at low field. The proposed sequence provides high sampling efficiency and improves temperature quantification via echo combination. The performance of the sequence was tested in healthy volunteer measurements in the absence of heating.
Majeed et al. (Wed,) studied this question.