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Three-dimensional (3D) dual-echo steady-state (DESS) MRI can produce multi-contrast (MC)images with T2 and diffusion weighting (DW) for simultaneous T2 and D mapping in knee and prostate. A primary challenge of MC DESS is the low signal-to-noise ratio (SNR) of DW DESS leads to less reliable diffusion mapping. In this work, we investigated a new random matrix theory-based denoising reconstruction to improve MC T2W/DW DESS by taking advantages of the inherent redundancy in noise statistics across multiple coil channel and contrasts dimensions. Our in-vivo knee and prostate experiments showed promising improvements in SNR and quality of T2 and D mapping.
Zhang et al. (Wed,) studied this question.