Differentiation of High-Grade Gliomas from Solitary Brain Metastases in the Peritumoral Edema: using Combined Synthetic MRI and 3D-pCASL

The main work of our research was to investigate the difference of quantitative MR metrics from synthetic MRI and 3D-pCASL including T1, T2, PD, CBF, and the multiparametric strategies that contained more than one of the metrics between high-grade gliomas (HGGs) from solitary brain metastases (SBMs) in the peritumoral edema. We found that the T1, T2, and CBF were useful metrics for differentiating HGGs from SBMs which were easily confounded with HGGs in daily diagnosis. Furthermore, combining T1, T2, and CBF further improved their diagnostic performance.