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Multi echo gradient echo (GRE) sequence is usually used in lower extremity BOLD experiments. This study replaced the GRE acquisition by SMS EPI and achieved broader coverage and higher temporal and spatial resolution. The minimum ischemia value (MIV) during the ischemia session and the R2* change rate (Grad) during the reperfusion session were calculated. Both MIV and Grad present muscle group-wise distribution. This study demonstrated the feasibility of the SMS GRE-EPI sampling strategy in the skeletal muscle BOLD experiment.
Qu et al. (Wed,) studied this question.
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