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Relaxation parameters T1 and T1ρ have shown promising results for endogenous assessment of myocardial tissue. However, mapping of the whole moving heart is challenging. This study proposes a novel free-breathing joint T1 and T1ρ mapping technique with near-isotropic spatial resolution, whole left ventricle coverage and short acquisition time of 5-6min. A diaphragmatic navigator was leveraged for prospective motion correction and retrospective motion mitigation. The T1ρ preparation module was optimized to be robust to field inhomogeneities and applicable to 3T. Phantom results indicated good accuracy of the proposed technique, and in vivo feasibility was demonstrated in healthy subjects.
Qi et al. (Wed,) studied this question.