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3D EPI is a clinically promising alternative for susceptibility weighted imaging due to multi-shot acceleration. However, achieving submillimeter resolution with 3D EPI is challenging as shot-to-shot B0 variations result in artifactual images that limit detection of small veins which can be decisive for detection of the central vein sign in multiple sclerosis. FID navigators have been shown to estimate phase drifts in EPI sequences. We demonstrate that FID-navigated 3D EPI acquisitions enable correction for phase-induced distortions and achieve high-quality submillimeter-resolution susceptibility weighted images.
Ütkür et al. (Wed,) studied this question.