A Simulation Study of the Effect of Sampling Strategy on Computation of T2 Maps

This work presents a simulation study on the differences between data from accelerated T2 mapping experiments vs T2w imaging studies. Subspace constrained and model-based reconstruction were tested on trajectories that exhibited narrow k-space sampling at each window, energy differences across echoes related to the k-space collected by each echo, and small total data size. Energy differences had the largest impact on T2 map reconstruction, and both methods were unsuitable for reconstructing T2w data that combined all features. This highlights the need for tailored reconstruction approaches, such as e-CAMP, to reconstruct T2 maps from T2w data.