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p53 genotyping is important for EC lymph node metastasis and prognosis determination. Multimodal MRI techniques APTw, T2 mapping, mDIXON-Quant and DWI are new tools to determine p53 genotyping. Results of this study indicate the APT value and R2* value in the p53abn group were higher than those in the p53wt group, while the ADC value was lower than those in the p53wt group. Therefore, APTw, mDIXON-Quant and DWI techniques can quantitatively identify p53abn and p53wt EC, it provides a new way for preoperative quantitative evaluation of EC molecular typing.
Zongyuan et al. (Wed,) studied this question.