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Cardiac pulsatility is a key driver of brain pulsatility. However, changes in brain pulsatility in response to changes in heart rate have been sparsely studied. Using a combination of amplified MRI and phase-contrast MRI, brain parenchyma motion, blood flow, and CSF flow were measured and assessed during rhythmic hand-grip exercise to help understand the role of heart rate on brain physiology. This approach opens opportunities for probing the role of heart rate, brain fluid, and motion flow in various pathologies that affect the brain.
Kumar et al. (Wed,) studied this question.