Feasibility of integrating 6 diffusion models within a single acquisition and their performance comparison in liver fibrosis staging

DWI has been broadly used in clinical practice, which can provide quantitative parameters. Several DWI models have been used for liver fibrosis staging but diagnostic performance variance in different research because their acquisitions are different and normally difficult to be compared in one study. In this study, we compared 6 DWI models, including 14 parameters in detecting significant liver fibrosis using date from one acquisition. The results showed that the DWI models were similarly valuable in detecting significant liver fibrosis in patients with liver disease. The combined index with the three parameters of CTRW model had the highest AUC.