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In this study, we explored the feasibility of dynamic glucose enhanced (DGE) MRI technology in the clinical application of gliomas. 20 glioma patients underwent pre-operative DGE-MRIs before clinical intervention. We observed a significant increase in DGE area under the uptake curve (AUC) signal in tumors compared to the white matter. In some cases, we found enhancement in DGE MRI in histopathological confirmed tumor region that was not enhanced by Gd T1w MRI. These findings provide a new perspective for the further exploration and analysis of the D-glucose delivery, uptake and metabolism in brain tumors.
Mo et al. (Wed,) studied this question.