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BACKGROUND The purpose of this study was to conduct a systematic review of Internet-based teleinterventions for patients with hypertension and to evaluate the cost-effectiveness of Internet-based teleinterventions for the management of hypertension. OBJECTIVE The purpose of this study was to conduct a systematic review of Internet-based teleinterventions for patients with hypertension and to evaluate the cost-effectiveness of Internet-based teleinterventions for the management of hypertension. METHODS A computerized search of the literature on health economics studies of remote interventions for hypertensive patients via the Internet in national and international databases was conducted from database construction to March 2023, and a qualitative systematic evaluation was performed by 2 researchers after independently screening the literature, extracting information, and evaluating the risk of bias of included studies. The risk of bias evaluation referred to the entries in the Consensus of Health Economic Evaluation Reporting Standards 2022 (CHEERS 2022) list that addressed the risk of bias. RESULTS The final 14 included literature on Internet-based remote blood pressure monitoring systems, mobile applications, and e-mail blood pressure management;7 literature underwent cost-benefit analysis, 3 literature underwent cost-utility analysis, 1 literature underwent cost-effectiveness analysis, and 1 literature underwent both cost-effectiveness analysis and cost-utility analysis; 2 literature conducted both cost effectiveness and cost-utility analysis; A total of 8 studies modeled health economics. all studies used quality-adjusted life-years as the primary output outcome indicator and 88% of the studies considered the intervention cost-effective and concluded that the teleintervention increased Quality-adjusted life years（QALY）; there were also cost-effectiveness analysis studies that included systolic blood pressure and blood pressure control rates, new cardiovascular events as health output indicators.An assessment of the included literature based on CHEERS 2022 found that the quality of included studies was high. CONCLUSIONS The current study allows to conclude that Internet-based remote intervention for hypertensive patients may be economical and effective in controlling blood pressure levels and improving the quality of life of hypertensive patients. The number of studies on the economics of Internet-based remote interventions for hypertension is high, but the quality of some of them needs to be improved, and there is still a need for higher quality, larger samples, and more standardized health economics evaluation studies to provide evidence for policy makers in the future. CLINICALTRIAL
娜 李 (Wed,) studied this question.