122 Monkeypox Correlations: Genital Symptoms, Immunocompromised Status and MSM

Abstract Aim The outbreak of the virus infection Monkeypox (Mpox) in England was on transmission level 2. Mpox and HIV infections may occur simultaneously among the MSM population, exacerbating the symptoms along with treating problems. We aimed to study if Mpox painful genital symptoms correlated with immunocompromised status, sexuality and length of hospital stay. Method A retrospective data analysis was conducted. The admissions were divided into four groups named: perianal, penile, rectal, and other symptoms. Correlations between patients’ pain groups, sexuality, or immunocompromised status as well as length of hospital stay were studied. Significances were computed by Spearman’s rho correlation and Kruskal-Wallis H analyses of variance. Results Sixty-nine patients were included, 65 males (mean age=38,5, SD 8.29; Md=39) and females mean age=35.5 (SD 9.04; Md= 39.5) years (n.s). The two gender’s Mpox pain areas differed from each other (p=0.014). A total of 38% of the men presented painful perianal or rectal lesions and 22 men displayed general symptoms and 17 acknowledged MSM. A total of 40% of the men were sexually active with multiple partners; an inverse correlation between men with MSM and men with HIV (rho 25= -.385*, p= .029, 1-tailed) was revealed. Altogether 23% of men presented HIV and 8% suffered from additional STI. Those with rectal pain had the longest hospital stay with a mean of 6.0 (SD 7.63) days (p=0.017) compared to other groups. Conclusions Correlations between patients diagnosed with Mpox and genital symptoms were revealed as opposed to inverse correlations between immunocompromised status/HIV and MSM.