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Type III Loeys-Dietz Syndrome (LDS) is a rare and progressive connective tissue disorder with a significant impact on the cardiovascular system. We report a case of a 47-year-old male diagnosed with type III LDS, who presented with a complex array of cardiovascular pathologies, such as aneurysmal dilatation of the aortic root and ascending aorta, along with annular dilatation and regurgitation of the aortic, mitral, and tricuspid valves. Genetic testing played a crucial role in establishing the diagnosis. A multivalvular surgical correction improved the patient's cardiac function and overall condition.
MIRONENKO et al. (Sun,) studied this question.