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Numerous studies emphasize the pivotal role of inflammation in metabolic dysfunction-associated steatotic liver disease (MASLD) development. Some link specific systemic immune biomarkers (e.g., systemic immuno-inflammatory index SII, neutrophil-to-albumin ratio NPAR and neutrophil-to-lymphocyte ratio NLR) to hepatic steatosis risk. However, the relevance of other markers like systemic immune-inflammation index SIRI, platelet-to-lymphocyte ratio PLR and lymphocyte/monocyte ratio LMR in MASLD remains unclear. Limited literature covers all six markers together. This study aims to investigate the association between SII, SIRI, LMR, NLR, PLR, and NPAR and MASLD, assessing their predictive value.
Wang et al. (Wed,) studied this question.
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