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Crohn's disease perianal fistulae are often resistant to standard anti-TNF-α therapies. Mesenchymal stem cell (MSC)-derived exosomes are extracellular vesicles that have highly potent anti-inflammatory effects, and the previous phase of this study demonstrated their safety in the treatment of refractory perianal fistulas.
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Alireza Hadizadeh
NorthShore University HealthSystem
Reza Akbari-asbagh
Asieh Heirani‐Tabasi
Shahid Beheshti University of Medical Sciences
Diseases of the Colon & Rectum
University of Chicago
Tehran University of Medical Sciences
NorthShore University HealthSystem
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Hadizadeh et al. (Fri,) studied this question.
synapsesocial.com/papers/68e59206b6db64358752d874 — DOI: https://doi.org/10.1097/dcr.0000000000003502